Big4Bio Case Study

Transforming Biotech News Aggregation for Digital Growth

Big4Bio, the leading news aggregator for biotech professionals, partnered with Agency 39A to revitalize its digital presence. Strategic SEO enhancements, improved technology, and the introduction of enhanced marketing tech positioned Big4Bio for sustainable growth.

140%

Increase in first-page keywords

9,000

Pages consolidated

29,000
Technical errors resolved

The Challenge

Despite its loyal subscriber base, Big4Bio struggled to translate this success into its digital presence. The website suffered from low engagement and poor visibility, with SEO rankings lagging behind competitors. Compounding these issues was a value proposition that failed to emphasize Big4Bio’s unique offerings. Outdated content and technical issues further undermined usability and discoverability. As competitors delivered more polished digital experiences, it became clear that a comprehensive overhaul was necessary to maintain Big4Bio’s position as a trusted leader in the biotech sector.

Our Approach

To address these challenges, we conducted a thorough analysis of Big4Bio and it's supporting digital platforms. This process included stakeholder interviews, comprehensive SEO and technical audits, and user journey mapping. Our research revealed significant gaps in keyword rankings, technical performance, and user engagement. Additionally, we uncovered unmet user needs, such as improved event tracking, more effective networking tools, and better access to historical data.

With these insights, we developed a strategy focused on resolving immediate pain points while laying the groundwork for sustainable, long-term improvements.

Key Solutions and Execution

Our work began by improving critical SEO and technical issues. Over 9,000 underperforming pages were consolidated into just 100 high-value pages, significantly improving navigation and crawl efficiency. We resolved nearly 29,000 technical errors, resulting in a dramatic improvement in page speed scores, which rose from 36 to 88. These changes delivered a seamless and more accessible user experience.

We introduced new features including a dedicated events page, searchable news archives, and automated newsletter previews. These updates addressed core user needs while reinforcing Big4Bio’s role as a go-to resource for biotech professionals. Trust-building elements, including testimonials, sponsor logos, and user statistics, were added to strengthen credibility and reinforce Big4Bio’s authority in the industry.

Finally, we migrated the site to Webflow, a modern, cloud-based CMS, and away from WordPress. This move eliminated reliance on outdated third-party plugins, reducing costs while improving security, performance, and scalability.

Results

Big4Bio’s transformation delivered tangible results. SEO performance improved significantly, with first-page keyword rankings increasing by 140%, including 17 non-branded terms directly targeting their audience. Navigation and content clarity were dramatically improved, offering users a more intuitive and seamless experience. The transition to a modern CMS enhanced scalability and eliminated the technical limitations that had previously hindered the platform.

The addition of features like the events page and networking tools created new opportunities for user engagement, firmly establishing Big4Bio as an indispensable resource in the biotech community.

Future Growth

With its digital foundation strengthened, Big4Bio is well-positioned for sustained growth. Plans are underway to introduce personalized news recommendations and interactive maps, further enhancing the user experience. Expanded SEO efforts will drive additional organic traffic, while the development of premium offerings aims to convert free subscribers into paying members.

This transformation has allowed Big4Bio to elevate its digital presence, deepen audience engagement, and reaffirm its role as a leader in biotech news. These changes are just the beginning of a new chapter in Big4Bio’s journey toward sustained growth and success.

What our clients say

“Working with Agency 39A on the development of our new website was a terrific experience. It is very challenging to find a marketing agency that can design and develop a new website that combines the art and science required in today’s world. Agency 39A did that for us, and while doing so, made the experience enjoyable. Everyone we interacted with was friendly, kind, on-time, and knew their stuff.”

STEVEN CURRY, CEO

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MUSTARDSEED

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“Agency 39A’s expertise in design and development - paired with their strong understanding of the healthcare industry - has made them a perfect fit partner for San Ysidro Health. The team is professional, responsive, knowledgeable, and kind. With their help, we’ve revolutionized our digital presence for patients and are already seeing the benefits!”

Brett Phillips, Business Implementation Director

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SAN YSIDRO HEALTH

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